The effect of prior COVID-19 infection on coronary microvascular dysfunction

Autor: Önder Bilge, Murat Çap, Ferat Kepenek, Emrah Erdogan, İsmail Tatlı, Cansu Öztürk, Ercan Taştan, Cihan Gündoğan, Ferhat Işık, Metin Okşul, Mesut Oktay, Halil Akın, Cengiz Burak, Mehmet Zülküf Karahan, Halil Kömek, İbrahim Halil Tanboğa
Rok vydání: 2022
Předmět:
Zdroj: Acta cardiologica.
ISSN: 1784-973X
Popis: Background Thrombolysis in Myocardial Infarction Frame Count (TFC) is an index that provides a quantitative evaluation of coronary microvascular dysfunction. In this study, we aimed to examine the effect of COVID-19 infection on TFC in patients admitted with chest pain and dyspnoea after COVID-19 disease and had abnormal findings in myocardial perfusion scintigraphy. Methods For this single-center retrospective study, patients with and without a history of COVID-19 who were underwent coronary angiography for abnormal findings in myocardial perfusion scintigraphy between January 1, 2021 and June 30, 2021 were analysed. Patients were divided into two groups as patients with COVID-19 history and those without. After exclusion criteria, patients with adequate angiographic monitoring and data were included in the study. Results A total of 210 patients, 48 with a history of COVID-19, were included in the study. The mean age was +/- 55 10 years, and 122 (58%) patients were women. In patients with a history of COVID-19, TFC was significantly higher in the LAD (p < 0.001) and LCx (p < 0.001) arteries and RCA TFC (p = 0.223) was similar in both groups. In the linear mix model, male gender (beta = 2.38, 95% CI = 1.26-3.51, p < 0.001) and history of COVID-19 (beta = 1.51, 95% CI = 0.49-2.53, p = 0.004) were significantly associated with TFC. Conclusion TFC may be elevated due to coronary microvascular dysfunction in patients with a history of COVID-19.
Databáze: OpenAIRE