Spheno-orbital meningiomas: outcome after microsurgical treatment: a clinical review of 30 cases
| Autor: | Ina Sterker, Jürgen Meixensberger, Bernhard Frerich, Susanne Honig, Ralf Schober, Christos Trantakis |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Microsurgery medicine.medical_specialty genetic structures medicine.medical_treatment Visual impairment Neurosurgical Procedures Sphenoid Bone Meningeal Neoplasms medicine Humans Aged Retrospective Studies business.industry Retrospective cohort study General Medicine Middle Aged Neurovascular bundle eye diseases Visual field Surgery Radiation therapy Treatment Outcome medicine.anatomical_structure Neurology Cavernous sinus Optic nerve Orbital Neoplasms Female Neurology (clinical) medicine.symptom Meningioma business Orbit (anatomy) |
| Zdroj: | Neurological Research. 32:314-325 |
| ISSN: | 1743-1328 0161-6412 |
| Popis: | Spheno-orbital meningiomas represent a delicate subtype of intracranial meningiomas involving the sphenoid wing, orbit and important neurovascular structures such as cavernous sinus, carotid artery or optic nerve. Insidious and aggressive dural, bone and orbital involvement contains several defiances to adequate resection, which provides high rates of recurrence.This retrospective case analysis consisted of 30 patients, who were surgically treated for spheno-orbital meningiomas performing a fronto-pterional approach by or under the supervision of the senior author (J. Meixensberger) between May 2001 and February 2006. There were 22 woman and eight men with a mean age of 54.4 years. The follow-up period ranged from 3 to 75 months (mean: 33.7 months).The majority of patients presented with a clinical triad of visual impairment (74%), progressive proptosis (55%) and visual field defects (40%). Total microscopic tumor resection was achieved in ten patients (33%). Visual acuity improved in 65% of the patients, and 40% of these returned to normal vision. Pre-existing cranial nerve deficits remained unchanged in the majority of patients (88%) and improved in 12%. Temporary new cranial nerve deficits occurred in three patients. The rate of permanent non-visual morbidity was 10% (three of 30 patients). Eight patients (27%) received post-operative radiotherapy with an overall tumor growth control rate of 63%. The overall recurrence rate was 27% (eight of 30 patients).Sufficient tumor control can be achieved with minimal morbidity and satisfying functional results. |
| Databáze: | OpenAIRE |
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