Utility of sonographically guided biopsy in metabolically suspected recurrent lymphoma
| Autor: | Rachel Bar Shalom, Diana Gaitini, Yehudith Ben-Arie, Zofia Levy, Ora Israel, Michalle Soudack |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Open biopsy Lymphoma Biopsy Computed tomography Sensitivity and Specificity Diagnosis Differential Fluorodeoxyglucose F18 Predictive Value of Tests Medicine Humans Radiology Nuclear Medicine and imaging In patient Ultrasonography Interventional Aged Retrospective Studies Fluorodeoxyglucose Aged 80 and over Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Middle Aged medicine.disease Predictive value Positron emission tomography Female Radiology Neoplasm Recurrence Local Radiopharmaceuticals business Tomography X-Ray Computed medicine.drug Tomography Emission-Computed |
| Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. 27(2) |
| ISSN: | 0278-4297 |
| Popis: | Objective. The purpose of this study was to determine the diagnostic accuracy of sonographically guided biopsy of [ 18 F]fluorodeoxyglucose (FDG)-avid foci on positron emission tomography (PET)/computed tomography (CT) in patients with lymphoma. Methods. We retrospectively reviewed the medical records of 56 patients with lymphoma (25 male and 31 female; mean age, 48.5 years; range, 22-80 years) who underwent sonographically guided biopsy of hypermetabolic FDG-avid foci precisely localized by PET/CT. Biopsies were performed up to 3 months after PET/CT. The accuracy of core biopsy was calculated and compared with clinical follow-up and histopathologic results of open biopsy. Results. Sixty-six sonographically guided biopsies were performed in the 56 patients. Histopathologic results were conclusive in 53 (80%) of 66. No complications occurred during or after the procedure. The overall sensitivity, specificity, positive predictive value, and accuracy for diagnosis of lymphoma were 100%, 95%, 97%, and 98%, respectively. Conclusions. Sonographically guided biopsy is a safe and effective means for investigating metabolically active lesions on FDG-PET/CT in patients with known lymphoma. |
| Databáze: | OpenAIRE |
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