In vivo MR spectroscopic imaging of the prostate, from application to interpretation
| Autor: | Arend Heerschap, Nassim Tayari, Thiele Kobus, Tom W. J. Scheenen |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Proton Magnetic Resonance Spectroscopic Imaging Magnetic Resonance Spectroscopy Biophysics Biochemistry Models Biological 030218 nuclear medicine & medical imaging 03 medical and health sciences Prostate cancer 0302 clinical medicine Nuclear magnetic resonance Prostate Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15] medicine Animals Humans Molecular Biology business.industry Magnetic resonance spectroscopic imaging Prostatic Neoplasms Cell Biology medicine.disease Mr imaging Magnetic Resonance Imaging 3. Good health medicine.anatomical_structure Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] Mr spectroscopic imaging Prostate gland business 030217 neurology & neurosurgery |
| Zdroj: | Analytical Biochemistry, 529, pp. 158-170 Analytical Biochemistry, 529, 158-170 |
| ISSN: | 0003-2697 |
| Popis: | Contains fulltext : 177776.pdf (Publisher’s version ) (Open Access) Proton magnetic resonance spectroscopic imaging (1H MRSI) enables non-invasive assessment of certain metabolites in the prostate gland. Several studies have demonstrated that this metabolic information, in combination with anatomical information from T2-weighted MR imaging significantly improves prostate cancer detection, localization and disease characterization. The technology of 1H MRSI is continuously evolving with improvements of hardware and acquisition methods. Recently, 31P and 13C MRSI of the prostate have regained new interest after a dormant period of decades. This review focuses on recent technical progress of in vivo1H MRSI of the prostate, in particular those that enhance clinical applicability at 3T with respect to commonly used techniques to examine the prostate. These developments consist of higher magnetic field strengths, and better MR coils and acquisition techniques. Besides the improvements for 1H MRSI, the developments and opportunities for 31P and 13C MRSI for the prostate are reviewed. Finally, we briefly review 13C MRS of the prostate, in particular the new possibilities with hyperpolarized substrates. |
| Databáze: | OpenAIRE |
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