The Times They Are a-Changin': Carbapenems for Extended-Spectrum-β-Lactamase-Producing Bacteria
| Autor: | Jesús Rodríguez-Baño |
|---|---|
| Přispěvatelé: | [Rodriguez-Bano,J] Unidad Clínica de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospitales Universitarios Virgen Macarena and Virgen del Rocío, Seville, Spain. Departamento de Medicina, Universidad de Sevilla, Seville, Spain., Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, European Development Regional Fund 'A way to achieve Europe' ERDF, Spanish Network for the Research in Infectious Diseases (REIPI RD12/0015), and Innovatives Medicine Initiative (IMI), European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies (COMBACTE, COMBACTE-CARE and COMBACTE-MAGNET projects, grant agreements 1155223, 115620, and 115737). |
| Rok vydání: | 2015 |
| Předmět: |
Lactams
Inhibidores de betalactamasas Context (language use) Microbial Sensitivity Tests beta-Lactamases Carbapenémicos Microbiology Enterobacteriaceae Chemicals and Drugs::Organic Chemicals::Amides::Lactams [Medical Subject Headings] Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams [Medical Subject Headings] polycyclic compounds Medicine Pharmacology (medical) Cephamycins Beta-Lactamase Inhibitors Organisms::Bacteria::Gram-Negative Bacteria::Gram-Negative Facultatively Anaerobic Rods::Enterobacteriaceae [Medical Subject Headings] Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Cephalosporins::Cephamycins [Medical Subject Headings] Pharmacology Cefamicinas biology business.industry biochemical phenomena metabolism and nutrition Beta-lactamas bacterial infections and mycoses Antimicrobial biology.organism_classification Anti-Bacterial Agents Infecciones por enterobacteriaceae Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Gram-Negative Bacterial Infections::Enterobacteriaceae Infections [Medical Subject Headings] Infectious Diseases Carbapenems Commentary bacteria beta-Lactamase Inhibitors business Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Carbapenems [Medical Subject Headings] Bacteria |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 59:5095-5096 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.01333-15 |
| Popis: | Several antimicrobial agents are being investigated as alternatives to carbapenems in the treatment of infections caused by ESBL-producing Enterobacteriaceae , which may be useful in avoiding overuse of carbapenems in the context of recent global spread of carbapenem-resistant Enterobacteriaceae . The most promising candidates for invasive infections so far are β-lactam/β-lactamase inhibitor combinations and cephamycins. |
| Databáze: | OpenAIRE |
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