Morphometric analysis of the endometrium of infertile patients in relation to peripheral hormone levels
| Autor: | Annette Bonhoff, Elisabeth Johannisson, Heinz G. Bohnet |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Ovulation medicine.medical_specialty Menotropins media_common.quotation_subject Uterus Physiology Stimulation Biology Luteal phase Endometrium Chorionic Gonadotropin Clomiphene Internal medicine Biopsy medicine Humans Menstrual Cycle Progesterone media_common Estradiol medicine.diagnostic_test Obstetrics and Gynecology medicine.anatomical_structure Endocrinology Reproductive Medicine In utero Female Infertility Female Hormone |
| Zdroj: | Fertility and Sterility. 54:84-89 |
| ISSN: | 0015-0282 |
| Popis: | In an attempt to identify factors that may be responsible for reproductive failure, we compared endometrial biopsies taken from infertile patients during the luteal phase of spontaneous cycles (n = 18) with those taken after ovarian stimulation (n = 18). Morphometric analyses were performed and compared with peripheral estradiol (E 2 ) and progesterone levels at the time of supposed implantation. In stimulated cycles the number of glands per square millimeter was positively correlated to the E 2 level. The morphometric data point to a measurable difference between the study groups, indicating an insufficient secretory transformation of the tissue in infertile women when compared with a group of fertile women. The observations suggest that hormonal stimulation occasionally results in impaired development of the endometrial glands. |
| Databáze: | OpenAIRE |
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