Epilepsy in the first 10 years of life: findings of the child health and education study
| Autor: | Euan Ross, C M Verity, Jean Golding |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Time Factors Developmental Disabilities Population Cohort Studies Epilepsy Recurrence Risk Factors Epidemiology medicine Humans education Child General Environmental Science Cause of death Family Health education.field_of_study Seizure types business.industry Learning Disabilities Incidence (epidemiology) Incidence General Engineering Age Factors Infant Symptomatic seizures General Medicine medicine.disease United Kingdom Child Preschool General Earth and Planetary Sciences Female business Cohort study Research Article |
| Zdroj: | University of Bristol-PURE |
| ISSN: | 0959-8138 |
| Popis: | OBJECTIVES--To identify children with afebrile seizures in a national cohort, classify the seizures, and document progress in the first 10 years of life. DESIGN--Population based birth cohort study. SETTING--The child health and education study, which includes 16,004 neonatal survivors (98.5% of infants born in the United Kingdom during one week of April 1970). SUBJECTS--14,676 children for whom relevant information was available. MAIN OUTCOME MEASURES--Responses to parental and general practitioner questionnaires and hospital records at 5 and 10 years after birth. RESULTS--84 children (42 boys, 42 girls) had had one or more afebrile seizure (incidence 5.7/1000). 63 children (31 boys, 32 girls) had epilepsy (incidence 4.3/1000). 49 of 55 children had a second seizure within a year of the first. The commonest seizure types were tonic-clonic (42) and complex partial (25). A greater proportion of children with complex partial seizures had recurrences. Children who had infantile spasms or a mixed seizure disorder had a poor outcome. All six children who died had symptomatic seizures in the first year, but seizures were not the direct cause of death. CONCLUSIONS--The results of this study are probably representative of seizure patterns in the general population. Outcome after seizures is determined more by the underlying disease than by the seizures themselves. |
| Databáze: | OpenAIRE |
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