Subtype C/CRF01_AE recombinant HIV-1 found in Thailand
| Autor: | Mark S. deSouza, Narongrid Sirisopana, Francine E. McCutchan, Deborah L. Birx, Veerachai Watanaveeradej, Eric Sanders-Buell, Jean K. Carr, Michael Benenson, Sorachai Nitayaphan, Penprapa Chanbancherd, Arthur E. Brown |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male Genes Viral viruses Immunology HIV Infections Gp41 Polymerase Chain Reaction Genome Virus law.invention law Humans Immunology and Allergy Typing Polymerase chain reaction Recombination Genetic Base Sequence Molecular epidemiology biology Thailand biology.organism_classification Virology Infectious Diseases Lentivirus HIV-1 Recombinant DNA |
| Zdroj: | AIDS. 17:2138-2140 |
| ISSN: | 0269-9370 |
| Popis: | The first HIV-1 recombinant between CRF01―AE and subtype C, NP1809, has been identified in Thailand. The nearly full genome was polymerase chain reaction amplified, sequenced and phylogenetically analysed. NP1809 was a complex recombinant, with at least 15 breakpoints. Gag and gp120 were subtype C, whereas pol and intracellular gp41 were CRF01―AE. We report a new inter-subtype recombinant of CRF01―AE and subtype C, establishing for the first time the presence of subtype C genetic material in Thailand. |
| Databáze: | OpenAIRE |
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