Tip-to-Base LAMPOON for Transcatheter Mitral Valve Replacement With a Protected Mitral Annulus
| Autor: | Brian Whisenant, Pradeep Yadav, Gaetano Paone, Paul Mahoney, James M. McCabe, Jaffar M. Khan, John Lisko, Jose F. Condado, Adam Greenbaum, Norihiko Kamioka, Ramzi Khalil, Jasleen Tiwana, Patrick Gleason, Toby Rogers, Neal S. Kleiman, Michael J. Reardon, Sachin S. Goel, Kendra J. Grubb, Krishna Cherukuri, Robert J. Lederman, David Lasorda, Rachel Koch, Vasilis Babaliaros, Brian C. Case, David V. Daniels, Christopher G Bruce, Christian Spies, Isida Byku |
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| Rok vydání: | 2021 |
| Předmět: |
Aortic valve
Cardiac Catheterization medicine.medical_specialty medicine.medical_treatment Ventricular outflow tract obstruction Investigational device exemption 030204 cardiovascular system & hematology Prosthesis Article Ventricular Outflow Obstruction 03 medical and health sciences 0302 clinical medicine Aortic valve replacement Valve replacement medicine Humans cardiovascular diseases 030212 general & internal medicine Retrospective Studies Heart Valve Prosthesis Implantation Mitral regurgitation business.industry Mitral valve replacement Mitral Valve Insufficiency medicine.disease Surgery Treatment Outcome medicine.anatomical_structure Heart Valve Prosthesis cardiovascular system Mitral Valve medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | JACC Cardiovasc Interv |
| ISSN: | 1936-8798 |
| DOI: | 10.1016/j.jcin.2020.11.034 |
| Popis: | Objectives The purpose of this study was to evaluate tip-to-base intentional laceration of the anterior mitral leaflet to prevent left ventricular outflow tract obstruction (LAMPOON) in patients undergoing transcatheter mitral valve replacement (TMVR) in annuloplasty rings or surgical mitral valves. Background LAMPOON is an effective adjunct to TMVR that prevents left ventricular outflow tract obstruction (LVOTO). Laceration is typically performed from the base to the tip of the anterior mitral leaflet. A modified laceration technique from leaflet tip to base may be effective in patients with a prosthesis that protects the aortomitral curtain. Methods This is a multicenter, 21-patient, consecutive retrospective observational cohort. Patients underwent tip-to-base LAMPOON to prevent LVOTO and leaflet overhang, or therapeutically to lacerate a long anterior mitral leaflet risking or causing LVOTO. Outcomes were compared with findings from patients in the LAMPOON investigational device exemption trial with a prior mitral annuloplasty. Results Twenty-one patients with a annuloplasty or valve prosthesis–protected mitral annulus underwent tip-to-base LAMPOON (19 preventive, 2 rescue). Leaflet laceration was successful in all and successfully prevented or treated LVOTO in all patients. No patients had significant LVOTO upon discharge. There were 2 cases of unintentional aortic valve injury (1 patient underwent emergency transcatheter aortic valve replacement and 1 patient underwent urgent surgical aortic valve replacement). In both cases, the patients had a supra-annular ring annuloplasty, and the retrograde aortic guiding catheter failed to insulate the guidewire lacerating surface from the aortic root. All patients survived to 30 days. Compared with classic retrograde LAMPOON, there was a trend toward shorter procedure time. Conclusions Tip-to-base laceration is a simple, effective, and safe LAMPOON variant applicable to patients with an appropriately positioned mitral annular ring or bioprosthetic valve. Operators should take care to insulate the lacerating surface from adjacent structures. |
| Databáze: | OpenAIRE |
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