Investigation of mammalian lignan precursors in flax seed: first evidence of secoisolariciresinol diglucoside in two isomeric forms by liquid chromatograph/mass spectrometry
| Autor: | Silvia A. Coron, Gloriano Moneti, P. Traldi, Caterina Ghiara, Andrea Raffaelli, Massimo Bambagiotti-Alberti |
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| Rok vydání: | 1994 |
| Předmět: |
Lignan
Chromatography Organic Chemistry Diastereomer Spectrometry Mass Fast Atom Bombardment Mass spectrometry Secoisolariciresinol diglucoside Lignans Analytical Chemistry Stereocenter chemistry.chemical_compound chemistry Enterolactone Glucosides Isomerism Liquid chromatography–mass spectrometry Seeds Organic chemistry Spectrophotometry Ultraviolet Enterodiol Butylene Glycols Spectroscopy Chromatography High Pressure Liquid |
| Zdroj: | Rapid communications in mass spectrometry : RCM. 8(12) |
| ISSN: | 0951-4198 |
| Popis: | A strong research effort has been devoted in recent years to the mammalian lignans enterolactone and enterodiol because of their claimed protective effects against breast and colon cancer. Some plant lignans appear to be precursors of these molecules. This paper reports a novel identification procedure for one of these precursors, the secoisolariciresinol diglucoside, in the extracts of defatted flax-seed meal. The procedure is based on high-performance liquid chromatography coupled with either ionspray or continuous-flow fast-atom bombardment mass spectrometry. The application of these techniques allowed the identification in flax seed of two isomeric forms of this precursor for the first time. The isomers are reasonable the two diastereoisomers, due to the two equivalent stereogenic centers present in the molecule. |
| Databáze: | OpenAIRE |
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