Genome‐wide association analyses of lesion counts in group‐housed pigs

Autor: Juan P. Steibel, Janice M. Siegford, Nancy E. Raney, Ronald O. Bates, C. W. Ernst, Kaitlin E Wurtz
Rok vydání: 2018
Předmět:
Zdroj: Animal Genetics. 49:628-631
ISSN: 1365-2052
0268-9146
DOI: 10.1111/age.12713
Popis: Aggression in group-housed pigs is a welfare concern and can negatively affect production. Skin lesions are reliable indicators of aggression and are moderately heritable, suggesting that selective breeding may reduce aggression. To further understand the genetic control of behavioral traits, such as the aggressive response to regrouping, associated single nucleotide polymorphisms (SNPs) can be identified within the genome, and the region in which these SNPs are located can be related to known genes. To investigate SNPs associated with aggression, 1093 purebred Yorkshire pigs were strategically remixed into new groups of familiar and unfamiliar animals at three life stages and lesion counts were recorded. Genomic best linear unbiased prediction (GBLUP) models were fitted for each trait. The genetic additive effect was obtained from a genetic relationship matrix constructed from the 50 924 SNPs. SNP effects and their variances were estimated from the GBLUP objects. SNPs that were associated with a significant portion of the trait variance were identified for lesions to the anterior (three SNPs, FDR
Databáze: OpenAIRE
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