A Preliminary Study of the Therapeutic Role of Human Early Fetal Aorta-derived Endothelial Progenitor Cells in Inhibiting Carotid Artery Neointimal Hyperplasia
| Autor: | Peng Liu, Rongwei Xu, Honglin Liu, Chang-An Yu, Jianbin Zhang, Lin Pan, Jinning Lou, Jianyan Wen, Meng Wang, Wenjian Zhang |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Cell Transplantation Cell Survival lcsh:Medicine Endothelial progenitor cell Carotid Artery Injury Endothelial Progenitor Cell Human Fetal Aorta Neointima Rats Sprague-Dawley Restenosis medicine.artery Cell Adhesion Animals Humans Medicine Progenitor cell Endothelial Progenitor Cells Neointimal hyperplasia Aorta business.industry lcsh:R Balloon catheter General Medicine medicine.disease Immunohistochemistry Rats Endothelial stem cell Transplantation Carotid Arteries surgical procedures operative Microscopy Fluorescence embryonic structures cardiovascular system Original Article business |
| Zdroj: | Chinese Medical Journal, Vol 128, Iss 24, Pp 3357-3362 (2015) Chinese Medical Journal |
| ISSN: | 0366-6999 |
| Popis: | Background: Endothelial cell damage is an important pathophysiological step of restenosis after angioplasty and stenting. Cell transplantation has great therapeutic potential for endothelial recovery. We investigated the effect of transplanting endothelial progenitor cells (EPCs) derived from human early fetal aortas in rat injured arteries. Methods: The carotid arterial endothelium of Sprague-Dawley rats was damaged by dilatation with a 1.5 F balloon catheter, and then EPCs derived from human early fetal aortas ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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