Essential fatty acids: the effects of dietary supplementation among children with recurrent respiratory infections
| Autor: | Bettelli F, C Spanò, E Turchetto, A Venuta, L Laudizi, A Beverelli |
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| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Randomization Linolenic acid Linoleic acid Physiology 030204 cardiovascular system & hematology Placebo Biochemistry Linoleic Acid 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Immune system Double-Blind Method Recurrence medicine Humans Respiratory system Respiratory Tract Infections chemistry.chemical_classification Cross-Over Studies business.industry Biochemistry (medical) Respiratory disease alpha-Linolenic Acid Cell Biology General Medicine medicine.disease Surgery chemistry Linoleic Acids 030220 oncology & carcinogenesis Child Preschool Female business Polyunsaturated fatty acid |
| Zdroj: | The Journal of international medical research. 24(4) |
| ISSN: | 0300-0605 |
| Popis: | The impact of dietary supplementation with essential fatty acids (EFA) on recurrent respiratory infections (RRI) in children was evaluated by means of a randomized crossover double-blind study. Linoleic acid (596 mg/day) and alpha-linolenic acid (855 mg/day) as a commercial preparation or placebo (olive oil) were administered for two consecutive winter seasons (November to February, T0– T120) to 20 children affected by RRI, aged between 36 and 49 months. Plasma levels of n-3 and n-6 metabolites increased after the administration of EFA. The number of infective episodes, days' fever and days' absence from school were reduced significantly during the observation period (extended from T120to T180) in children receiving EFA supplementation. Our results suggest that n-3 and n-6 polyunsaturated fatty acids may play a favourable role in the defence mechanism of these subjects. |
| Databáze: | OpenAIRE |
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