Latent, sex-specific metabolic health effects in CD-1 mouse offspring exposed to PFOA or HFPO-DA (GenX) during gestation
Autor: | Suzanne E. Fenton, Vesna A. Chappell, Bevin E. Blake, Harlie A. Cope, Charlotte Love, Susan A. Elmore, James McCord, Janice B. Harvey |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
GenX Offspring Gestational exposure Health Toxicology and Mutagenesis PFAS Adipose tissue White adipose tissue Urine Toxicology Environmental pollution Article chemistry.chemical_compound Internal medicine medicine Weaning business.industry PFOA Public Health Environmental and Occupational Health Metabolism Endocrinology TD172-193.5 chemistry HFPO-DA Perfluorooctanoic acid Gestation Microvesicular fatty change medicine.symptom business Weight gain |
Zdroj: | Emerging contaminants Emerging Contaminants, Vol 7, Iss, Pp 219-235 (2021) |
ISSN: | 2405-6650 |
DOI: | 10.1016/j.emcon.2021.10.004 |
Popis: | Background: Perfluorooctanoic acid (PFOA) is an environmental contaminant associated with adverse metabolic outcomes in developmentally exposed human populations and mouse models. Hexafluoropropylene oxide-dimer acid (HFPO-DA, commonly called GenX) has replaced PFOA in many industrial applications in the U.S. and Europe and has been measured in global water systems from |
Databáze: | OpenAIRE |
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