More vasomotor symptoms in menopause among women with a history of hypertensive pregnancy diseases compared with women with normotensive pregnancies
| Autor: | Angela H.E.M. Maas, Yvonne T. van der Schouw, Gerrie-Cor M. Herber-Gast, José T. Drost |
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| Rok vydání: | 2013 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Physical examination Body Mass Index Pregnancy Risk Factors Surveys and Questionnaires medicine Humans Gynecology Cardiovascular diseases [NCEBP 14] medicine.diagnostic_test Vasomotor Obstetrics business.industry Obstetrics and Gynecology Hypertension Pregnancy-Induced Odds ratio Middle Aged medicine.disease Vasomotor System Menopause Cardiovascular Diseases Hot Flashes Cohort Female Waist Circumference business Body mass index Blood sampling |
| Zdroj: | Menopause-The Journal of the North American Menopause Society, 20, 10, pp. 1006-11 Menopause-The Journal of the North American Menopause Society, 20, 1006-11 |
| ISSN: | 1072-3714 |
| Popis: | Item does not contain fulltext OBJECTIVE: Cardiovascular disease is the major cause of mortality in women worldwide. In recent years, several female-specific cardiovascular risk factors, such as hypertensive pregnancy diseases (HPDs) and vasomotor menopausal symptoms (VMS), have been identified. In this study, we evaluated the association between a history of HPD and the presence of VMS. METHODS: We consecutively included 853 women (mean age, 55.5 y) who visited the outpatient cardiovascular clinic for women in Kampen between 2003 and 2010. The visit included a questionnaire on history of HPD, demographic characteristics, and VMS; physical examination; and blood sampling. Logistic regression analysis was used to analyze the data. RESULTS: A history of HPD was reported by 274 women (32%), and VMS were reported by 83% of women with a history of HPD and by 75% of women without a history of HPD. In adjusted models, VMS were more often present (odds ratio [OR], 1.62; 95% CI, 1.00-2.63) and more frequently persisted for longer than 1 year (OR, 2.05; 95% CI, 1.08-3.89) among women with a history of HPD than among women with normotensive pregnancies. VMS were more often severe in women with a history of HPD, but this did not reach significance (adjusted OR, 1.28; 95% CI, 0.92-1.80). The frequency and intensity of VMS did not differ between both groups. CONCLUSIONS: In our "Kampen women cardiology clinic" cohort, women with a history of HPD report VMS during the menopausal transition significantly more often than women with normotensive pregnancies. |
| Databáze: | OpenAIRE |
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