Multiple acquired portosystemic shunts secondary to primary hypoplasia of the portal vein in a cat
| Autor: | Kazuyuki Uchida, Kenjiro Fukushima, Satoko Sugimoto, James K. Chambers, Kohei Saeki, Koichi Ohno, Hajime Tsujimoto, Shingo Maeda, Reina Fujiwara, Masaya Tsuboi, Naoaki Matsuki, Tomohiro Yonezawa |
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| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty 040301 veterinary sciences Vascular Malformations Encephalopathy hepatic encephalopathy Cat Diseases 0403 veterinary science medicine Internal Medicine Animals feline Hepatic encephalopathy General Veterinary medicine.diagnostic_test business.industry Portal Vein 0402 animal and dairy science portal hypertension Hyperammonemia 04 agricultural and veterinary sciences medicine.disease Note 040201 dairy & animal science Hypoplasia Dysplasia acquired portosystemic shunt Liver biopsy cardiovascular system Cats Portal hypertension Female Portosystemic shunt business microvascular dysplasia |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 |
| Popis: | A 6-year 5-month-old spayed female Scottish Fold cat presented with a one-month history of gait abnormalities, increased salivation, and decreased activity. A blood test showed hyperammonemia and increased serum bile acids. Imaging tests revealed multiple shunt vessels indicating acquired portosystemic shunt. Histopathologic analysis of liver biopsy showed features consistent with liver hypoperfusion, such as a barely recognizable portal vein, increased numbers of small arterioles, and diffuse vacuolar degeneration of hepatocytes. These findings supported the diagnosis of primary hypoplasia of the portal vein/microvascular dysplasia, (PHPV/MVD). To our knowledge, this is the first case of feline PHPV/MVD that developed multiple acquired portosystemic shunts and presented with hepatic encephalopathy. |
| Databáze: | OpenAIRE |
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