Additional file 7 of Head and neck squamous cell carcinoma cell lines have an immunomodulatory effect on macrophages independent of hypoxia and toll-like receptor 9

Autor: Ishizu, Tamiko, Eichin, Dominik, Padzik, Artur, Tuominen, Sanni, Grénman, Reidar, Salmi, Marko, Grönroos, Tove J., Tuomela, Johanna M.
Rok vydání: 2021
DOI: 10.6084/m9.figshare.16570136
Popis: Additional file 7. A summary of the CM-induced MΦ polarization phenotypes (a) CM-mediated hybridized MΦ polarization phenotype, demonstrates a direct mechanism cancer undertakes to evade anti-tumorigenic immune responses. Values represent MFI values normalized to non-activated MΦ (nMFI), n = 5–10. (b) Listed p-values describing the statistical significance of M1 (green), M2a (blue), and M2c (gray) marker expressions after exposure to the variety of CMs. The tint of the color signifies the direction of the expression: darker color represents a median expression (nMFI) above NA MΦ. Similarly, lighter color represents median expression below NA MΦ.
Databáze: OpenAIRE