Towards establishing a minimal nanoparticle concentration for applications involving surface enhanced spatially offset resonance Raman spectroscopy (SESORRS) in vivo
Autor: | Fay Nicolson, Duncan Graham, Neil C. Shand, Konstantinos Plakas, Samuel Mabbott, Lauren E. Jamieson, Karen Faulds, Michael R. Detty |
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Rok vydání: | 2018 |
Předmět: |
Offset (computer science)
Materials science Swine Resonance Raman spectroscopy Nanoparticle 02 engineering and technology 010402 general chemistry Spectrum Analysis Raman 01 natural sciences Biochemistry Analytical Chemistry symbols.namesake Heterocyclic Compounds 1-Ring In vivo Limit of Detection Organoselenium Compounds Electrochemistry Environmental Chemistry Animals QD Spectroscopy Detection limit business.industry Spatially offset Raman spectroscopy 021001 nanoscience & nanotechnology 0104 chemical sciences symbols Optoelectronics Nanoparticles 0210 nano-technology Raman spectroscopy business Raman scattering |
Zdroj: | The Analyst. 143(22) |
ISSN: | 1364-5528 0003-2654 |
Popis: | Resonant chalcogenpyrylium nanotags demonstrate an exceptional surface enhanced Raman scattering (SERS) performance for use in SORS applications. Using surface enhanced spatially offset Raman spectroscopy (SESORS), nanotags modified with a chalcogenpyrylium dye were observed at concentrations as low as 1 pM through 5 mm of tissue. Calculated limits of detection suggest that these SERS nanotags can be detected at 104 fM using surface enhanced spatially offset resonance Raman scattering (SESORRS) demonstrating their potential for in vivo applications. |
Databáze: | OpenAIRE |
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