Seasonality of distinct respiratory viruses in a tropical city: implications for prophylaxis

Autor: Cristiana M. Nascimento-Carvalho, Igor C. Borges, Mariana L. Souza, Ruth‐Kelly O. Santos, Maiara L. Bouzas
Rok vydání: 2021
Předmět:
Male
Seasonal distribution
viruses
030231 tropical medicine
Fluorescent Antibody Technique
Respiratory Syncytial Virus Infections
medicine.disease_cause
Real-Time Polymerase Chain Reaction
Virus
law.invention
Adenoviridae
03 medical and health sciences
0302 clinical medicine
law
Influenza
Human
medicine
Influenza A virus
Humans
Respiratory system
Direct fluorescent antibody
Polymerase chain reaction
Tropical Climate
Paramyxoviridae Infections
business.industry
Incidence
Public Health
Environmental and Occupational Health
virus diseases
Respiratory infection
Infant
Seasonality
medicine.disease
Virology
Parainfluenza Virus 1
Human
Parainfluenza Virus 2
Human
Parainfluenza Virus 3
Human
Respiratory Syncytial Viruses
Influenza B virus
Infectious Diseases
Cross-Sectional Studies
Child
Preschool
Parasitology
Female
Seasons
business
Brazil
Zdroj: Tropical medicineinternational health : TMIHReferences. 26(6)
ISSN: 1365-3156
Popis: OBJECTIVE The frequency and seasonality of viruses in tropical regions are scarcely reported. We estimated the frequency of seven respiratory viruses and assessed seasonality of respiratory syncytial virus (RSV) and influenza viruses in a tropical city. METHODS Children (age ≤ 18 years) with acute respiratory infection were investigated in Salvador, Brazil, between July 2014 and June 2017. Respiratory viruses were searched by direct immunofluorescence and real-time polymerase chain reaction for detection of RSV, influenza A virus, influenza B virus, adenovirus (ADV) and parainfluenza viruses (PIV) 1, 2 and 3. Seasonal distribution was evaluated by Prais-Winsten regression. Due to similar distribution, influenza A and influenza B viruses were grouped to analyse seasonality. RESULTS The study group comprised 387 cases whose median (IQR) age was 26.4 (10.5-50.1) months. Respiratory viruses were detected in 106 (27.4%) cases. RSV (n = 76; 19.6%), influenza A virus (n = 11; 2.8%), influenza B virus (n = 7; 1.8%), ADV (n = 5; 1.3%), PIV 1 (n = 5; 1.3%), PIV 3 (n = 3; 0.8%) and PIV 2 (n = 1; 0.3%) were identified. Monthly count of RSV cases demonstrated seasonal distribution (b3 = 0.626; P = 0.003). More than half (42/76 [55.3%]) of all RSV cases were detected from April to June. Monthly count of influenza cases also showed seasonal distribution (b3 = -0.264; P = 0.032). Influenza cases peaked from November to January with 44.4% (8/18) of all influenza cases. CONCLUSIONS RSV was the most frequently detected virus. RSV and influenza viruses showed seasonal distribution. These data may be useful to plan the best time to carry out prophylaxis and to increase the number of hospital beds.
Databáze: OpenAIRE
Externí odkaz: