Xerostomia, gustatory and olfactory dysfunctions in patients with COVID-19

Autor: Antonella Polimeni, Giuliano Bertazzoni, Daniele Corbi, Claudio Maria Mastroianni, Alessandro Villa, Riccardo Pampena, Salvatore Minisola, Stefano Mammucari, Emanuele Pampena, Federica Alessi, Domenico Di Vanna, Paolo Fantozzi, Eugenia Pellegrino, Umberto Romeo
Rok vydání: 2020
Předmět:
Male
Oral medicine
Disease
Severity of Illness Index
Cohort Studies
Olfaction Disorders
Taste Disorders
0302 clinical medicine
Surveys and Questionnaires
80 and over
Prevalence
Viral
030223 otorhinolaryngology
Aged
80 and over
Public health
Middle Aged
Infectious Diseases
Taste disorder
Italy
030220 oncology & carcinogenesis
Female
medicine.symptom
Coronavirus Infections
Cohort study
medicine.medical_specialty
National Health and Nutrition Examination Survey
Anosmia
Clinical Sciences
Pneumonia
Viral
and over
Dysgeusia
Xerostomia
Article
03 medical and health sciences
Betacoronavirus
COVID-19
public health
xerostomia
oral medicine
oral diseases
dysgeusia
anosmia
Internal medicine
Severity of illness
medicine
Oral diseases
Humans
Dental/Oral and Craniofacial Disease
Pandemics
Nutrition
Aged
Retrospective Studies
business.industry
SARS-CoV-2
Neurosciences
Retrospective cohort study
Pneumonia
Otorhinolaryngology
business
Mind and Body
Zdroj: American journal of otolaryngology, vol 41, iss 6
American Journal of Otolaryngology
ISSN: 1532-818X
Popis: BackgroundThe novel Coronavirus Disease-19 (COVID-19) continues to have profound effect on global health. Our aim was to evaluate the prevalence and characterize specific symptoms associated with COVID-19.MethodsThis retrospective study included 326 patients with confirmed SARS-CoV-2 infection evaluated at the Emergency Department of the Umberto I Polyclinic Hospital, Rome, Italy between March 6th and April 30th, 2020. In order to assess xerostomia, olfactory and gustatory dysfunctions secondary to COVID-19, a telephone-based a modified survey obtained from the National Health and Nutrition Examination Survey (NHANES) 2013-2014 for taste and smell disorders and the Fox Questionnaire for dry mouth were administered to 111 patients (34%) after discharge between June 4th and June 12th.ResultsTaste dysfunction was the most common reported symptom (59.5%; n=66), followed by xerostomia (45.9%; n=51) and olfactory dysfunctions (41.4%; n=46). The most severe symptom was olfactory dysfunction with a median severity score of 8.5 (range: 5-10). Overall 74.5% (n=38) of patients with xerostomia, 78.8% (n=52) of patients with gustatory dysfunctions and 71.1% (n=33) of patients with olfactory dysfunctions reported that all symptoms appeared before COVID-19 diagnosis. Overall, the majority of patients reported one symptom only (45.9%, n=51), 37 (33.3%) reported the association of two symptoms, and 23 (20.7%) patients reported the association of three symptoms at the same time.ConclusionXerostomia, gustatory and olfactory dysfunctions may present as a prodromal or as the sole manifestation of COVID-19. Awareness is fundamental to identify COVID-19 patients at an early stage of the disease and limit the spread of the virus.
Databáze: OpenAIRE
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