Inhaled Nitric Oxide in Patients with Severe Heart Failure: Changes in Lung Perfusion and Ventilation Detected Using Scintigraphy
| Autor: | Giovanni Ruvolo, Francesco Scopinaro, Giuseppe Speziale, S La Francesca, G. De Vincentis, Benedetto Marino, M. Ierardi, L. De Biase |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Pulmonary Circulation medicine.medical_specialty Hypertension Pulmonary medicine.medical_treatment Nitric Oxide Scintigraphy Nitric oxide chemistry.chemical_compound Internal medicine Administration Inhalation Ventilation-Perfusion Ratio medicine Humans Radionuclide Imaging Lung Aged Heart Failure Heart transplantation Dose-Response Relationship Drug medicine.diagnostic_test Inhalation business.industry Middle Aged medicine.disease Pulmonary hypertension medicine.anatomical_structure chemistry Heart failure Breathing Vascular resistance Cardiology Heart Transplantation Female Vascular Resistance Surgery Cardiology and Cardiovascular Medicine business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1439-1902 0171-6425 |
| DOI: | 10.1055/s-2007-1011980 |
| Popis: | Inhaled nitric oxide (NO) is a selective pulmonary vasodilator in patients with end-stage cardiac failure. Preoperative high pulmonary vascular resistance could modify early and late results after heart transplantation generally due to right-ventricular failure. Aim of this study was to assess pulmonary vascular resistance variability following inhalation of NO by using a scintigraphic method. Our preliminary results suggest that inhaled NO in patients with end-stage heart failure redistributes blood away from apical regions and towards more basal and posterior segments, probably dilating blood vessels in ventilated but nonperfused zones. NO may represent a simple and reliable method to evaluate dynamic response of pulmonary vasculature. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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