| Autor: |
José M. Quintana, Ane Antón-Ladisla, Nerea González, Santiago Lázaro, Marisa Baré, Nerea Fernández de Larrea, Maximino Redondo, Eduardo Briones, Antonio Escobar, Cristina Sarasqueta, Susana García-Gutierrez, Jose María Quintana López, Marisa Baré Mañas, Maximino Redondo Bautista, Eduardo Briones Pérez de la Blanca, Nerea Fernández de Larrea Baz, Cristina Sarasqueta Eizaguirre, Antonio Escobar Martínez, Francisco Rivas Ruiz, Maria M. Morales-Suárez-Varela, Juan Antonio Blasco Amaro, Isabel del Cura González, Inmaculada Arostegui Madariaga, Amaia Bilbao González, Nerea González Hernández, Susana García-Gutiérrez, Iratxe Lafuente Guerrero, Urko Aguirre Larracoechea, Miren Orive Calzada, Josune Martin Corral, Ane Antón-Ladislao, Núria Torà, Marina Pont, María Purificación Martínez del Prado, Alberto Loizate Totorikaguena, Ignacio Zabalza Estévez, José Errasti Alustiza, Antonio Z. Gimeno García, Santiago Lázaro Aramburu, Mercè Comas Serrano, Jose María Enríquez Navascues, Carlos Placer Galán, Amaia Perales, Iñaki Urkidi Valmaña, Jose María Erro Azkárate, Enrique Cormenzana Lizarribar, Adelaida Lacasta Muñoa, Pep Piera Pibernat, Elena Campano Cuevas, Ana Isabel Sotelo Gómez, Segundo Gómez-Abril, F. Medina-Cano, Julia Alcaide, Arturo Del Rey-Moreno, Manuel Jesús Alcántara, Rafael Campo, Alex Casalots, Carles Pericay, Maria José Gil, Miquel Pera, Pablo Collera, Josep Alfons Espinàs, Mercedes Martínez, Mireia Espallargues, Caridad Almazán, Paula Dujovne Lindenbaum, José María Fernández-Cebrián, Rocío Anula Fernández, Julio Ángel Mayol Martínez, Ramón Cantero Cid, Héctor Guadalajara Labajo, María Heras Garceau, Damián García Olmo, Mariel Morey Montalvo, Javier Mar |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
European Journal of Surgical Oncology. 44:1344-1353 |
| ISSN: |
0748-7983 |
| DOI: |
10.1016/j.ejso.2018.05.030 |
| Popis: |
Objective There is limited information on health service use or patient-reported outcomes when comparing the effectiveness of laparoscopic with that of open surgery. The aim was to compare the effectiveness of laparoscopic with that of open surgery up to 2 years after intervention in patients with colon cancer. Methods Prospective cohort study of patients with colon cancer who underwent surgery (laparoscopic or open surgery) between June 2010 and December 2012, at 22 hospitals. Main outcomes of the study were mortality, complications, reoperation, readmission, and patient-reported outcome measures (PROMs), as measured using the Hospital Anxiety and Depression Scale, Duke-UNC, EuroQol-5D, and European Organisation for Research and Treatment of Cancer-Q30 and Q29 at baseline, and 30 days and 1 and 2 years after surgery. Multivariable multilevel logistic regression and generalized linear models were used in analyses after adjusting for specific propensity scores developed for each outcome and time point. Results In the multivariable analysis, the complication rates up to 30 days (infectious, surgical, and medical) and 1 year (surgical), and readmission rate at 30 days and at 2 years were higher among patients who underwent open surgery than among those who underwent laparoscopic surgery. There were no differences between the two surgical approaches in all other parameters assessed and in changes of all PROMs. Conclusions Though in most outcomes both surgical approaches provide similar results up to 2 years after intervention, still the rates of some complications and readmission, mainly up to 30 days, are higher in open surgery. ClinicalTrials.gov Identifier NCT02488161 . |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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Full Text from ScienceDirect 