Number of high-protein containing meals correlates with muscle mass in pre-frail and frail elderly

Autor:	Lívia de Souza Gonçalves, Mariana Dutilh de Capitani, Ana Paula Hayashi, Samara Fernandes Dias, Davi Alves de Santana, Renato Tavares Dos Santos Pereira, Manoel E. Lixandrão, José Claudio Jambassi-Filho, Luiz Augusto Riani, Victoria Hevia-Larraín, Alan Lins Fernandes, Hamilton Roschel, Bruno Gualano, Rosa Maria Rodrigues Pereira
Rok vydání:	2020
Předmět:	0301 basic medicine Anabolism Frail Elderly health care facilities manpower and services Medicine (miscellaneous) Physiology 030209 endocrinology & metabolism Bench press 03 medical and health sciences 0302 clinical medicine Hand strength Humans Medicine Frail elderly Muscle Strength Muscle Skeletal Meals Postural Balance Aged Meal 030109 nutrition & dietetics Nutrition and Dietetics Hand Strength business.industry Muscles Confounding Middle Aged Time and Motion Studies Cohort Lean body mass business human activities
Zdroj:	European Journal of Clinical Nutrition. 74:1047-1053
ISSN:	1476-5640 0954-3007
Popis:	Aging is accompanied by the inability to optimally respond to anabolic stimulus of nutrition, with consequent loss of muscle mass and functionality. It has been speculated that not only total protein intake, but also the per meal protein dose may have important implications to protein balance and, hence, muscle mass in middle-aged and older adults, but evidence is lacking in a more vulnerable population such as the frail elderly. The aim was to investigate possible associations between total protein intake and its per meal dose with multiple measures of muscle mass, strength, and functionality in a cohort of pre-frail and frail elderly individuals. One-hundred-and-fifty-seven pre-frail and frail elderly individuals were assessed for total and per meal protein intake (food diaries), total and appendicular lean mass (DXA), vastus lateralis cross-sectional area [(CSA) B-mode ultrasound], and muscle function [leg-press and bench press 1-RM, timed-stands test, timed-up-and-go test, handgrip, and risk of falls (Biodex Balance System®)]. Protein intake and number of meals with either ≥20 g or ≥30 g of protein were significantly associated (after controlling for confounding factors) with greater total and appendicular lean mass and vastus lateralis CSA. We found that not only total protein intake but also the number of high-protein containing meals are associated with muscle mass in frail and pre-frail elderly.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c4bf04aecdde42f4cc24542f280779 https://doi.org/10.1038/s41430-020-0618-3 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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