Alcohol Consumption Among Pregnant Women in a Swedish Sample and Its Effects on the Newborn Outcomes
| Autor: | Viveka Sundelin-Wahlsten, Lars Oreland, Anders Helander, Erika Comasco, Gunilla Hallberg |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty Adolescent Alcohol Drinking Medicine (miscellaneous) Binge drinking Alcohol Toxicology Nicotine Young Adult chemistry.chemical_compound Pregnancy Surveys and Questionnaires medicine Humans Longitudinal Studies Young adult Psychiatry Retrospective Studies Sweden Alcohol Use Disorders Identification Test business.industry Obstetrics Infant Newborn Retrospective cohort study Middle Aged medicine.disease Psychiatry and Mental health chemistry Prenatal Exposure Delayed Effects Female Phosphatidylethanol business Biomarkers medicine.drug |
| Zdroj: | Alcoholism: Clinical and Experimental Research. 36:1779-1786 |
| ISSN: | 0145-6008 |
| Popis: | Background Little is known about the effects of low levels of maternal alcohol intake on the neuropsychological development of the child. This study is part of an ongoing investigation on maternal drinking and presents data on demographic variables, maternal alcohol use, and birth outcomes from that study. Methods The sample comprised 2,264 women from a Swedish antenatal clinic. Retrospective self-report data were collected on alcohol consumption before and during pregnancy, using the Alcohol Use Disorders Identification Test (AUDIT), and on nicotine use. Specific alcohol biomarkers for excessive drinking, carbohydrate-deficient transferrin (CDT) in serum and phosphatidylethanol (PEth) in whole blood, were determined during mid-pregnancy in a subsample of the women. Data on labor and early characteristics of the child were also assessed. Results Before pregnancy, 89% of the women regularly consumed alcohol and 49% reported occasional or frequent binge drinking. Nicotine was used by 15% before and by 5% during pregnancy. During pregnancy, 12% continued using alcohol and 5% also admitted binge drinking. However, all alcohol biomarker values were below the reporting limits (CDT = 1.7% disialotransferrin; total PEth < 0.1 mu mol/L). Self-reported drinking during pregnancy was associated with a higher AUDIT score before pregnancy, nicotine use at the time of the first prenatal visit, older age, and previous legal abortions. Conclusions The AUDIT questionnaire and 2 specific alcohol biomarkers were used in routine maternity care to collect information about drinking during pregnancy and thereby to identify children at risk for alcohol-related complications. While the AUDIT results suggested that a significant number of women continued using alcohol during pregnancy, implying a risk for fetal disorders, the biomarkers showed negative test values thus indicating only modest drinking levels. |
| Databáze: | OpenAIRE |
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