Limb regeneration inAmbystoma larvae during and after treatment with adult pituitary hormones
| Autor: | F. J. Chlapowski, Roy A. Tassava, Charles S. Thornton |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
medicine.medical_specialty
animal structures Period (gene) media_common.quotation_subject Urodela Adrenocorticotropic Hormone Pituitary Hormones Anterior Ambystoma maculatum Internal medicine Adrenal Glands medicine Animals Regeneration Transplantation Homologous Metamorphosis Hypophysectomy media_common Larva biology Adrenal cortex Metamorphosis Biological General Medicine biology.organism_classification body regions Endocrinology medicine.anatomical_structure Pituitary Gland Notophthalmus viridescens embryonic structures Pituitary hormones Animal Science and Zoology Hormone |
| Zdroj: | Journal of Experimental Zoology. 167:157-164 |
| ISSN: | 1097-010X 0022-104X |
| DOI: | 10.1002/jez.1401670204 |
| Popis: | Intact and hypophysectomized larvae of Ambystoma maculatum, A. opacum, A. laterale and A. mexicanum were subjected to the influence of adult newt (Notophthalmus viridescens) pituitary hormones by means either (1) of adenohypophyseal implants to the lower jaw or, (2) daily intraperitoneal injections of ACTH. After a 10–21 day treatment period, the ecotopic newt pituitary was removed or the ACTH injections were terminated. Neither procedure had any consequence for limb regeneration, whether limbs were amputated during, or from two to five days following cessation of, hormone treatment. The positive regenerative response suggests that limb tissues of larval Ambystoma do not respond either directly, or indirectly via the adrenal cortex, to the ectopic adult newt pituitary or to ACTH injection. Implanted adult newt pituitaries were found to cause precocious metamorphosis in A. maculatum, A. opacum, and A. laterale but not in A. mexicanum. |
| Databáze: | OpenAIRE |
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