Utilization of umbilical cord blood for the evaluation of group B streptococcal sepsis screening
| Autor: | Vinayak Govande, Cheryl Loughran, Cheryl Cipriani, Madhava R. Beeram |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Infant Premature Diseases Gastroenterology Umbilical cord Sensitivity and Specificity Umbilical vein Group B Streptococcus agalactiae Sepsis fluids and secretions Neonatal Screening Staphylococcus auricularis Internal medicine Streptococcal Infections medicine Humans Prospective Studies Leukopenia medicine.diagnostic_test biology business.industry Infant Newborn Complete blood count Reproducibility of Results Venous blood medicine.disease biology.organism_classification Fetal Blood Blood Cell Count medicine.anatomical_structure embryonic structures Pediatrics Perinatology and Child Health Immunology Female medicine.symptom business Infant Premature |
| Zdroj: | Clinical pediatrics. 51(5) |
| ISSN: | 1938-2707 |
| Popis: | Objective. To evaluate reliability of umbilical cord blood (UCB) for complete blood count (CBC) and blood cultures compared with the infant’s blood from peripheral site for group B streptococcal (GBS) sepsis screening. Methods. A total of 200 neonates, at risk for GBS infection, were studied prospectively. After birth, UCB sample was obtained for CBC and blood cultures from umbilical vein. Peripheral arterial/venous blood was obtained from the neonate. Results. In 200 neonates, CBC counts were similar for clinical significance except for leukopenia (6% in UCB vs 1.2% in peripheral blood, P = .02). One UCB sample grew GBS and another grew microaerophilic streptococcus, a contaminant. A neonatal sample grew Escherichia coli, a pathogen and another neonatal sample grew Staphylococcus auricularis, a contaminant. Conclusion. CBC results were similar from UCB and the infant for the purpose of GBS screening. Contamination of UCB sample for culture is uncommon. Hence, UCB may be used for GBS sepsis screen. |
| Databáze: | OpenAIRE |
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