Penoscrotal Paget's disease
| Autor: | S. Fouéré, J.-N. Dauendorffer, C. Lebbé, Barouyr Baroudjian, F. Herms, M. Bagot, Nicole Basset-Seguin, B. Cavelier-Balloy |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Paget's Disease Mammary Imiquimod Breast Neoplasms Dermatology Disease Adenocarcinoma 030207 dermatology & venereal diseases 03 medical and health sciences Prostate cancer 0302 clinical medicine Dermis Scrotum medicine Humans business.industry Cancer medicine.disease medicine.anatomical_structure Paget Disease Extramammary business Penis medicine.drug |
| Zdroj: | Annales de dermatologie et de venereologie. 148(2) |
| ISSN: | 0151-9638 |
| Popis: | Paget's disease (PD) denotes an initially intra-epidermal adenocarcinoma that can later invade the dermis and metastasise. Among the extramammary forms of PD (EMPD), penoscrotal presentations are rarer than the vulvar and perianal forms. Once diagnosis has been confirmed by histopathological examination, a search for associated neoplasia must be conducted, although penoscrotal EMPD is less frequently associated with underlying neoplasia than mammary PD (MPD). The associated cancer most often involves a neighbouring organ, with prostate cancer being the most common, or in some cases consists of underlying cutaneous adnexal tumours. First-line therapy consists of surgical excision. Alternatives to surgery (imiquimod, CO2 laser vaporisation, dynamic phototherapy) may be considered in certain cases. |
| Databáze: | OpenAIRE |
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