A rare case of antibody against enhancement media interfering with crossmatching: A case report and review of literature
| Autor: | Dibyajyoti Sahoo, B Abhishekh, S Anuragaa, Revathy Nair |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Blood transfusion
Routine testing biology business.industry medicine.medical_treatment Enhancement media Case Report Hematology pretransfusion testing Blood group antigens low-ionic strength solution Immunology Rare case medicine biology.protein Immunology and Allergy Diseases of the blood and blood-forming organs RC633-647.5 Indirect Antiglobulin Test Antibody business Direct antiglobulin test Antibody screening |
| Zdroj: | Asian Journal of Transfusion Science Asian Journal of Transfusion Science, Vol 15, Iss 1, Pp 100-103 (2021) |
| ISSN: | 1998-3565 0973-6247 |
| Popis: | Detection of clinically significant alloantibodies during pretransfusion testing is essential before any blood transfusion. Sometimes, clinically insignificant antibodies unrelated to blood group antigen may interfere with routine testing. Their interpretation is often made only after tedious immunohematology workup resulting in the exclusion of all possible clinically significant antibodies. We encountered such incidence which interfered with crossmatching. In our case, direct antiglobulin test was negative, indirect antiglobulin test and autocontrol were positive with pan-reactive antibody screening test, and group-specific units were incompatible. After meticulous workup, we could find that these antibodies were directed against the enhancement media, low-ionic strength solution in this case. |
| Databáze: | OpenAIRE |
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