Comparison of ciprofloxacin or trimethoprim therapy for venous leg ulcers: results of a pilot study
| Autor: | Saara Huovinen, Seppo Sarna, Inkeri Helander, Pirkko Kotilainen, Pentti Huovinen, Ken Malanin, Helinä Järvinen |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors medicine.drug_class Antibiotics Pilot Projects Dermatology Staphylococcal infections Trimethoprim Varicose Ulcer Double-Blind Method Ciprofloxacin Internal medicine medicine Humans Aged Aged 80 and over business.industry Osteomyelitis Middle Aged Staphylococcal Infections Antimicrobial medicine.disease Surgery Cellulitis Female business medicine.drug |
| Zdroj: | Journal of the American Academy of Dermatology. 31(2 Pt 1) |
| ISSN: | 0190-9622 |
| Popis: | The prevalence of leg ulcers varies from 0.6% to 1.15% in women 65 to 84 years of age and from 0.3% to 0.5% in men of similar age.' Most of the leg ulcers (80% to 90%) are of venous origin. Because local treatment is not always effective.r" uncomplicated leg ulcers (ulcers without cellulitis or osteomyelitis) are often treated with systemic antimicrobial agents. Although short-term antimicrobial therapy is ineffective.P preliminary evidence indicates that long-term ciprofloxacin therapy may be beneficial. 6 However, placebo-controlled trials with standardized local treatment, including compression bandages, have not been performed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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