Control of breathing in patients with chronic obstructive lung disease
| Autor: | J. Milic-Emili, J. Šorli, G. Lorange, A. Grassino |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Male Hypercapnia Functional residual capacity Tidal Volume Medicine Occlusion pressure Animals Humans In patient Lung Diseases Obstructive Lung Tidal volume Aged Breathing room air business.industry Respiration General Medicine Middle Aged medicine.disease Obstructive lung disease Low tidal volume Control of respiration Anesthesia Chronic Disease Female business Lung Volume Measurements |
| Zdroj: | Clinical science and molecular medicine. 54(3) |
| ISSN: | 0301-0538 |
| Popis: | 1. Using the mouth occlusion pressure technique, we have studied the control of breathing in seven hypercapnic and eight non-hypercapnic patients with chronic obstructive lung disease. 2. When breathing room air, pulmonary ventilation, mean inspiratory flow and P0·1 (mouth occlusion pressure developed 0·1 s after the onset of occluded inspiration at functional residual capacity) were not significantly different between the two groups of patients. Tidal volume, however, was significantly lower in the hypercapnic than in the non-hypercapnic patients, as a result of a significantly lower duration of inspiration. 3. The lower tidal volume in the hypercapnic patients leads to decreased alveolar ventilation, and appears to be the main cause of retention of carbon dioxide. |
| Databáze: | OpenAIRE |
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