Prediction of trimethoprim/sulfamethoxazole resistance in community-onset urinary tract infections
| Autor: | P. Brandon Bookstaver, Madeline DeMarsh, Julie Ann Justo, Majdi N. Al-Hasan, Joseph Kohn, Caroline Gordon, Juanne Lim, Nicole C. Griffith, Nicole K. Bookstaver |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male 0301 basic medicine Microbiology (medical) medicine.medical_specialty Urinary system 030106 microbiology Immunology Urine Antimicrobial stewardship Logistic regression Microbiology 03 medical and health sciences 0302 clinical medicine Enterobacteriaceae Internal medicine Trimethoprim Sulfamethoxazole Drug Combination Escherichia coli medicine Humans Immunology and Allergy 030212 general & internal medicine Urine culture Retrospective Studies biology Antibiogram business.industry Sulfamethoxazole Middle Aged biology.organism_classification Trimethoprim QR1-502 Anti-Bacterial Agents Case-Control Studies Urinary Tract Infections Ambulatory Female business medicine.drug |
| Zdroj: | Journal of Global Antimicrobial Resistance, Vol 21, Iss, Pp 218-222 (2020) |
| ISSN: | 2213-7165 |
| DOI: | 10.1016/j.jgar.2019.10.023 |
| Popis: | Objectives: This study aimed to predict trimethoprim/sulfamethoxazole (SXT) resistance in patients with community-onset urinary tract infection (UTI) due to Enterobacteriaceae based on patient-specific risk factors. Methods: This was a retrospective case–control study in Prisma Health facilities in central South Carolina, USA, including three community hospitals, affiliated emergency departments and ambulatory clinics, including adult patients with community-onset UTI due to Enterobacteriaceae (1 April 2015 to 29 February 2016). Multivariate logistic regression was used to examine risk factors for SXT resistance. Results: Among 351 unique patients with community-onset UTI, 71 (20.2%) had SXT-resistant Enterobacteriaceae urinary isolates. Overall, median age was 64 years and 252 (71.8%) were female. A multivariate model identified prior urinary infection/colonisation with SXT-resistant Enterobacteriaceae (OR = 8.58, 95% CI 3.92–18.81; P |
| Databáze: | OpenAIRE |
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