Transcatheter closure as standard treatment for most interatrial defects: experience in 200 patients treated with the Amplatzer Septal Occluder
| Autor: | Gregor Krings, Peter Ewert, Michael Vogel, Peter E. Lange, Felix Berger, P G Björnstad, Ingo Dähnert, I Brilla-Austenat |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Cardiac Catheterization Time Factors medicine.medical_treatment Atrial septal defects Heart Septal Defects Atrial Prosthesis Implantation Paradoxical embolism Internal medicine Occlusion medicine Humans Cardiac catheterization Heart septal defect Interventional cardiology business.industry Standard treatment General Medicine Prostheses and Implants medicine.disease Treatment Outcome Pediatrics Perinatology and Child Health Cardiology Female Stents Cardiology and Cardiovascular Medicine business Shunt (electrical) Follow-Up Studies |
| Zdroj: | Cardiology in the young. 9(5) |
| ISSN: | 1047-9511 |
| Popis: | To judge whether an Amplatzer™ Septal Occluder can be used as standard therapy instead of surgery for closure of atrial septal defects we report our experiences in 200 patients. Of these patients, 127 had an atrial septal defect with haemodynamically significant left-to-right shunt, 68 patients a persistent oval foramen after presumed paradoxical embolism, and 5 had a fenestration after Fontan-repair. Mean age was 29.8 years (0.8 to 77.7 years). Body weight ranged from 6.9 to 120.0 kg (mean 51.5 kg). After diagnostic cardiac catheterization, and balloon-sizing of the defect, we implanted Amplatzer™ Septal Occluders with stents of 4 to 28 mm diameter. Follow-up studies were obtained after 48hours, and one, six, and twelve months. Transcatheter closure of the atrial septal defect proved successful in all without any relevant residual shunts. In particular, complete closure was achieved in all patients after presumed paradoxical embolism. The mean period of follow-up is 9–5 months, with a range from 0.4 to 23.5 months, giving a total of 1898 patient months. The occlusion rate after three month was 98.1°. A trivial haemodynamically insignificant residual shunt remained in 1.9° of the patients. Fluoroscopy times ranged from 0 to 43.5 minutes, with a median of 8.7 minutes. The excellent results in the short and medium term in children and adults have resulted in using this device routinely at the present time for closure of central atrial septal defects up to a diameter of 28 mm. Final judgement, however, is only possible after long-term follow-up. |
| Databáze: | OpenAIRE |
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