Numerical Investigation of the Effects of Prosthetic Aortic Valve Design on Aortic Hemodynamic Characteristics
| Autor: | Joon-Hock Yeo, Xiao-Qin Shen, Ya-Li Su, Hai Huang, Guangyu Zhu, Cheng-Fu Yang |
|---|---|
| Přispěvatelé: | School of Mechanical and Aerospace Engineering |
| Rok vydání: | 2020 |
| Předmět: |
Aortic valve
Materials science single point attached commissures Flow distribution 0206 medical engineering Hemodynamics 02 engineering and technology 030204 cardiovascular system & hematology lcsh:Technology lcsh:Chemistry 03 medical and health sciences 0302 clinical medicine medicine.artery Ascending aorta Single Point Attached Commissures helical flow Shear stress medicine General Materials Science Prosthetic Aortic Valve lcsh:QH301-705.5 Instrumentation Fluid Flow and Transfer Processes Aorta hemodynamic environments lcsh:T Process Chemistry and Technology General Engineering Secondary flow wall shear stress 020601 biomedical engineering prosthetic aortic valve lcsh:QC1-999 Computer Science Applications medicine.anatomical_structure vortex lcsh:Biology (General) lcsh:QD1-999 lcsh:TA1-2040 Descending aorta Mechanical engineering [Engineering] lcsh:Engineering (General). Civil engineering (General) lcsh:Physics Biomedical engineering |
| Zdroj: | Applied Sciences, Vol 10, Iss 4, p 1396 (2020) Applied Sciences Volume 10 Issue 4 |
| ISSN: | 2076-3417 |
| DOI: | 10.3390/app10041396 |
| Popis: | The superior performance of single-point attached commissures (SPAC) molded valve design has been validated by several numerical, in vitro and in vivo animal studies. However, the impacts of the SPAC molded valve design on aortic hemodynamic environments are yet to be investigated. In this study, multiscale computational models were prepared by virtually implanting prosthetic aortic valves with SPAC tubular, SPAC molded and conventional designs into a patient-specific aorta, respectively. The impacts of the valve designs on efferent flow distribution, flow pattern and hemodynamic characteristics in the aorta were numerically investigated. The results showed that despite the overall flow phenomena being similar, the SPAC tubular valve exhibited a suboptimal performance in terms of higher spatially averaged wall shear stress (SAWSS) in ascending aorta (AAo), higher helix grade, stronger secondary flow mean secondary velocity in descending aorta, as well as more complex vortex distribution. The results from the current study extend the understanding of hemodynamic impacts of the valve designs, which would further benefit the optimization of the prosthetic aortic valve. Published version |
| Databáze: | OpenAIRE |
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