Diagnostic accuracy of stress myocardial perfusion imaging in Indian diabetic patients: A single centre experience
| Autor: | Padma A Namgyal, Sandeep Bansal, Ravinder S Sethi, Aditi K Sehgal, Tajamul Syed Malik, Deepa Kumar |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Coronary angiography
medicine.medical_specialty 030204 cardiovascular system & hematology 030218 nuclear medicine & medical imaging Coronary artery disease 03 medical and health sciences Myocardial perfusion imaging 0302 clinical medicine Internal medicine diabetic medicine Radiology Nuclear Medicine and imaging medicine.diagnostic_test myocardial perfusion SPECT business.industry Incidence (epidemiology) Retrospective cohort study Gold standard (test) medicine.disease Stenosis Cardiology Original Article Radiology business Perfusion coronary artery disease |
| Zdroj: | Indian Journal of Nuclear Medicine : IJNM : The Official Journal of the Society of Nuclear Medicine, India |
| ISSN: | 0972-3919 |
| DOI: | 10.4103/0972-3919.207873 |
| Popis: | Diabetics have around 2-4 times increased risk of coronary artery disease(CAD) and it is the most important cause of mortality in these patients. This study was carried out to compare the sensitivity, specificity and accuracy of MPI-SPECT among diabetics and non-diabetics in the Indian population. Material and Methods: This retrospective study included 261 patients; 213 males and 48 females, with 75 diabetic and 186 non-diabetic patients. Only type II diabetics and non-diabetic patients were included in the study. Only patients who had coronary angiography (CAG) done within 6 months of the stress 99mTc-sestamibi MPI-SPECT study were included in the study. Two arbitrary cut off points on CAG ≥ 50% and ≥ 70% were used for determination of extent of CAD. Results: Considering coronary angiography as gold standard with ≥ 50% coronary stenosis as a cut off criteria for significant stenosis the sensitivity and specificity respectively, of myocardial perfusion SPECT was 83% and 72% in diabetics and 81% and 69% in non-diabetic pateints (p value not significant). For ≥ 70% coronary stenosis as a cut off criteria for significant stenosis the sensitivity and specificity respectively, of myocardial perfusion SPECT was 87% and 61% in diabetics and 88% and 58%in non-diabetics (p value not significant). No significant difference was found in the sensitivity, specificity and accuracy of LAD, LCx and RCA coronary vessels among diabetics and non-diabetics for both ≥ 50% and ≥ 70% coronary stenosis as cut off criteria. Diabetic patients had a lower incidence of SVD compared to the non-diabetic patients. They also had a higher incidence of TVD and MVD compared to the non-diabetic patients with both ≥ 50% and ≥ 70% diameter stenosis criteria (p value significant). Conclusion: Sensitivity and specificity of 99mTc-sestamibi myocardial perfusion imaging is similar in diabetic and non-diabetic patients in Indian population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|