Complex Fibroadenoma with Pronounced Squamous Metaplasia: A Rare Case Report, Differential Diagnostic Considerations, and Associated Breast Cancer Risk
| Autor: | Danielle Robinson Petty, Wencheng Li, Christopher Humphries |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Breast lesion Breast Neoplasms Epithelial atypia Pathology and Forensic Medicine Diagnosis Differential Breast cancer Rare case medicine Humans skin and connective tissue diseases Retrospective Studies Metaplasia business.industry medicine.disease Squamous metaplasia stomatognathic diseases Fibroadenoma Sclerosing adenosis Carcinoma Squamous Cell Female Surgery Anatomy Complex Fibroadenoma business |
| Zdroj: | International Journal of Surgical Pathology. 30:227-231 |
| ISSN: | 1940-2465 1066-8969 |
| DOI: | 10.1177/10668969211035842 |
| Popis: | Squamous metaplasia of the breast is a rare and unusual finding. A number of benign and malignant differential entities exist when squamous cells are present in a breast lesion. Our patient was found to have pronounced squamous metaplasia and keratin cysts arising in a complex fibroadenoma. The rare nature of squamous metaplasia arising in such a lesion poses some diagnostic challenges, as squamous epithelium and squamous metaplasia in the breast may raise suspicion for malignancy. Herein we present a unique case and discussion of benign and malignant differential entities. We also retrospectively reviewed a series of complex fibroadenomas in our institution, including the demographic and histologic features, and more importantly the associated breast cancer risk. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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