Comparison of Measurement Methods for Dermal Exposure to Hazardous Chemicals at the Workplace: The SysDEA Project
| Autor: | Rianda Gerritsen-Ebben, Ulrich Poppek, Dag Rother, Suzanne Spaan, Pelagia Anastasiadou, Ilianna Chartzala, Remy Franken, Gianna Lucadei, Urs Schlüter, Anja Baumgärtel, Kyriaki Machera, Konstantinos M. Kasiotis, Michael Roitzsch, Angelos N. Tsakirakis |
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| Rok vydání: | 2019 |
| Předmět: |
Context (language use)
Comparison 010501 environmental sciences 01 natural sciences Dermal exposure Hazardous Substances Specimen Handling Workplace exposure 03 medical and health sciences 0302 clinical medicine Occupational hygiene Hazardous waste Occupational Exposure Ddermal exposure assessment Humans 0105 earth and related environmental sciences Skin Measurement method Reproducibility Public Health Environmental and Occupational Health Sampling (statistics) Reproducibility of Results Contamination Pulp and paper industry Hand 030210 environmental & occupational health Environmental science Experiments Gloves Protective Dermal exposure measurement methods |
| Zdroj: | Annals of work exposures and health, 1, 64, 55-70 |
| ISSN: | 2398-7316 |
| Popis: | There is a principal need for more precise methodology with regard to the determination of occupational dermal exposure. The goal of the Systematic analysis of Dermal Exposure to hazardous chemical Agents at the workplace project was therefore to generate scientific knowledge to improve and standardize measurement methods for dermal exposure to chemicals at the workplace. In addition, the comparability of different measurement methods was investigated. Different methods (body sampling by means of coveralls and patches, hand sampling by means of gloves and washing, and head sampling by means of headbands and wiping) were compared. Volunteers repeatedly performed a selection of tasks under standardized conditions in test chambers to increase the reproducibility and decrease variability. The selected tasks were pouring, rolling, spraying, and handling of objects immersed in liquid formulations, as well as dumping and handling objects contaminated with powder. For the chemical analysis, the surrogate test substance Tinopal SWN was analyzed by means of a high-performance liquid chromatographic method using a fluorescence detector. Tinopal SWN was either applied as a solid product in its pure form, or as a low and high viscosity liquid containing Tinopal SWN in dissolved form. To compare the sampling methods with patches and coveralls, the exposure values as measured on the patches were extrapolated to the surface areas of the respective parts of the coverall. Based on this extrapolation approach, using the patch method resulted in somewhat higher exposure values compared to using a coverall for all exposure situations, but the differences were only statistically significant in case of the liquid exposure situations. Using gloves resulted in significantly higher exposure values compared to hand wash for handling immersed objects, rolling, and handling contaminated objects, and slightly higher (not significant) exposure values during pouring and spraying. In the same context, applying wipe sampling resulted in higher exposure values than using a headband, which was at least partly due to extrapolation of the wipe results to the surface area of the headband. No 'golden standard' with regard to a preferred measurement method for dermal exposure could be identified from the methods as investigated in the current study. © The Author(s) 2019. Published by Oxford University Press on behalf of the British Occupational Hygiene Society. |
| Databáze: | OpenAIRE |
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