Is maternal serum creatine kinase actually a marker for early diagnosis of ectopic pregnancy?
| Autor: | Monique Dehoux, G.Durand Gaucher, Jacqueline Hassid, Emile Darai, Didier Sitbon, Jean Louis Benifla, E. Nunez, Georges Vlastos, P. Madelenat |
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| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
Serum progesterone chemistry.chemical_compound Pregnancy Reference Values medicine Humans Statistical analysis Chorionic Gonadotropin beta Subunit Human Prospective Studies Prospective cohort study Creatine Kinase Progesterone Gynecology Creatinine Ectopic pregnancy biology business.industry Obstetrics Obstetrics and Gynecology medicine.disease Pregnancy Ectopic Reproductive Medicine chemistry biology.protein Serum creatine kinase Creatine kinase Female Abortion Missed business Biomarkers |
| Zdroj: | European journal of obstetrics, gynecology, and reproductive biology. 68(1-2) |
| ISSN: | 0301-2115 |
| Popis: | Objective: Our purpose was to investigate whether serum creatine kinase (CK) levels could be used as an early marker of ectopic pregnancy. Student's t -test was used for statistical analysis. Study design: In a prospective study we therefore measured serum progesterone, βhCG and CK levels in 30 women with ectopic pregnancies, 30 women with ongoing pregnancies and 30 women with missed abortion. Results: The mean serum CK concentration for patients with an ectopic pregnancy, ongoing pregnancy, and the women with missed abortion was 81.4 ± 66.2, 81.5 ± 40.3, 84.8 ± 49.3, respectively. No relationship was found between CK level and the location of the pregnancy. Conclusion: Conversely to the first report of Lavie et al. (Am J Obstet Gynecol 1993; 169: 1149), our data suggest that serum CK level is not discriminative in the early diagnosis of tubal pregnancy. |
| Databáze: | OpenAIRE |
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