Neurothekeoma of the Cornea
| Autor: | Hans E. Grossniklaus, Alan M. Kozarsky, Mina M. Naguib, Caroline Craven |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Myxoma Histogenesis medicine.disease 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Cornea 030221 ophthalmology & optometry medicine Immunohistochemistry Neoplasm business Pathological Case Series and Brief Reports General Nursing Neurothekeoma Immunostaining |
| Popis: | Neurothekeomas (NTKs) are benign cutaneous neoplasms of fibrohistiocytic origin and most commonly occur in the head, neck, and upper extremities. Traditionally, NTK and nerve sheath myxoma (NSM) were classified as subtypes of a single neoplasm with a common histogenesis, but recently immunostaining has demonstrated that the lesions are most likely of distinct cellular origin. Rarely, NTKs have been reported to occur in the ocular adnexa, and the present case of a 39-year-old female is the first to describe a cellular NTK originating in the cornea and mimicking a Salzmann's nodular degeneration. This report describes the clinical and pathological findings of the patient, discusses the changes in the classification of these rare neoplasms in light of advances in immunohistochemistry, and reviews all cases of ocular NTK found in the literature. |
| Databáze: | OpenAIRE |
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