A Fuzzy Model of Glucose Regulation

Autor: Terry W. Martin, Em Ward
Rok vydání: 2006
Předmět:
Zdroj: Journal of Medical Systems. 30:187-203
ISSN: 1573-689X
0148-5598
DOI: 10.1007/s10916-005-7983-2
Popis: We present a detailed glucose regulation model using fuzzy inference system (FIS) descriptions of hormonal control action and the familiar Michaelis---Menten (M---M) kinetic description for glucose transport. The fuzzy M---M model is compared and contrasted with a well-known comprehensive glucose model. The two models give similar results for glucose response, endogenous glucose production, and total uptake. The fuzzy M---M model features a renal subsystem that provides 25% of the endogenous glucose production. The work demonstrates the successful application of fuzzy logic and fuzzy inference to biological modelling. The flexibility of fuzzy inference, a linguistic description technique, permits conceptually simple statements about nonlinear processes.
Databáze: OpenAIRE