Association of Abnormal Liver Function Parameters with HIV Serostatus and CD4 Count in Antiretroviral-Naive Rwandan Women
| Autor: | Kathryn Anastos, Donald R. Hoover, Victorien Ndacyayisenga, Emmanuel Rudakemwa, Léonard Gakindi, Jean d’Amour Sinayobye, Michael Mulvihill, Eugene Mutimura, Emmanuel Musabeyezu, Jean Claude Dusingize, Qiuhu Shi |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
medicine.medical_specialty Immunology Serum albumin HIV Infections Outcomes Research Liver Function Tests Virology Internal medicine Prevalence Medicine Humans Aspartate Aminotransferases Prospective Studies Prospective cohort study Serum Albumin biology medicine.diagnostic_test business.industry Liver Diseases Rwanda virus diseases Alanine Transaminase Middle Aged 3. Good health CD4 Lymphocyte Count Infectious Diseases Alanine transaminase Cohort biology.protein Female Abnormality business Liver function tests Risk assessment Serostatus |
| Zdroj: | AIDS Research and Human Retroviruses |
| ISSN: | 1931-8405 |
| Popis: | We determined the associations of HIV infection/CD4 count with markers of hepatocellular damage [elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT)] and liver synthetic function (decreased albumin) in HIV-infected (HIV+) antiretroviral therapy (ART)-naive and uninfected (HIV−) Rwandan women. In 2005, 710 HIV+ ART-naive and 226 HIV− women enrolled in the Rwanda Women's Interassociation Study and Assessment. Liver enzymes were measured with abnormality defined as either AST or ALT ≥1.25 times the upper limit of normal. Low serum albumin level was defined as 350 (p |
| Databáze: | OpenAIRE |
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