Association of perceived stress with health status outcomes in patients with peripheral artery disease
| Autor: | Merrill Thomas, Jeremy Provance, William R. Hiatt, Clementine Labrosciano, Qurat-ul-ain Jelani, Herbert D. Aronow, Ali O. Malik, Kim G. Smolderen, Poghni A. Peri-Okonny, John A. Spertus, Phillip G Jones, Kensey Gosch, Carlos Mena-Hurtado |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Arterial disease Health Status Perceived Stress Scale Disease Severity of Illness Index Article Cohort Studies Peripheral Arterial Disease 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus medicine Humans Chronic stress In patient Prospective Studies Registries 030212 general & internal medicine Socioeconomic status Aged business.industry medicine.disease Psychiatry and Mental health Clinical Psychology Cohort Female business Stress Psychological 030217 neurology & neurosurgery |
| Zdroj: | J Psychosom Res |
| ISSN: | 0022-3999 0141-9080 |
| DOI: | 10.1016/j.jpsychores.2020.110313 |
| Popis: | Objective To assess association of chronic self-perceived stress with health status outcomes of patients with peripheral artery disease. Methods The PORTRAIT study is a prospective registry that enrolled 1275 patients with symptoms of peripheral artery disease across 16-sites in US, Netherlands, and Australia from June 2011 to December 2015. Demographics, comorbidities and diagnostic information was abstracted from chart review. Self-perceived stress was assessed using the 4-item perceived stress scale at baseline, 3- and 6-month follow-up. Scores range from 0 to 16 with higher scores indicating greater stress. Sum scores were calculated at each time point and averaged to quantify average exposure to stress from enrollment through 6 months. Disease-specific health status were assessed at baseline and 12-months using the peripheral artery disease questionnaire summary score. Results The mean age of the analytical cohort (n = 1060) was 67.7 ± 9.3 years, 37.1% were females, and 82.3% were white. Comorbidities were highly prevalent with 80.9% having hypertension, 32.6% having diabetes, and 36.4% being smokers. In models adjusted for demographics, comorbidities, disease severity and socioeconomic status, having a higher average stress score was associated with poorer recovery (from baseline) in peripheral artery disease questionnaire summary score at 12-months (−1.4 points per +1-point increase in averaged 4-point perceived stress score, 95% CI -2.1, −0.6 p Conclusion In patients with peripheral artery disease, experiencing higher chronic stress throughout the 6-months following their diagnosis, was independently associated with poorer recovery in 12-month disease-specific health status outcomes. ( ClinicalTrial.gov identifier: NCT01419080 ). |
| Databáze: | OpenAIRE |
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