(2R,3R,4S,5R)-2-(4-Amino-5-iodo-7H-pyrrolo-[2,3-d]pyrimidin-7-yl)-5-methyl-tetra-hydro-furan-3,4-diol

Autor:	Ulrich Flörke, Birte Drewes
Rok vydání:	2013
Předmět:	Crystallography biology Hydrogen bond Diol General Chemistry Dihedral angle Condensed Matter Physics Ring (chemistry) Bioinformatics biology.organism_classification Organic Papers Crystal Bond length chemistry.chemical_compound chemistry QD901-999 Furan Tetra ddc:530 General Materials Science
Zdroj:	Acta Crystallographica Section E: Structure Reports Acta crystallographica / E E69, 01646-01647 (2013). doi:10.1107/S1600536813027931 Acta Crystallographica Section E, Vol 69, Iss 11, Pp o1646-o1647 (2013)
ISSN:	1600-5368
Popis:	The molecular structure of the title compound, C11H13IN4O3, shows a ribofuranosyl–pyrrolo O—C—N—C torsion angle of 59.1 (3)°, with the central C—N bond length being 1.446 (3) Å. The C—I bond length is 2.072 (2) Å. The amino group is coplanar with the attached aromatic ring [C—N—C—N torsion angle = −178.8 (2)°] and forms an intramolecular N—H...I hydrogen bond. In the crystal, O—H...N and N—H...O hydrogen bonds link the molecules into puckered layers parallel to (001). These layers are bound to each other by secondary I...O interactions [3.2250 (17) Å], forming a three-dimensional framework.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8558dabf9cf91149ebfa0f141a11cfd https://pubmed.ncbi.nlm.nih.gov/24454089 Zobrazit plný text záznamu