Three-Dimensional Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging Investigation of Inner Ear Disturbances in Cases of Middle Ear Cholesteatoma With Labyrinthine Fistula

Autor: Terukazu Mizuno, Makoto Sugiura, Tsutomu Nakashima, Shinji Naganawa, Michihiko Sone
Rok vydání: 2007
Předmět:
Zdroj: Otology & Neurotology. 28:1029-1033
ISSN: 1531-7129
DOI: 10.1097/mao.0b013e3181587d95
Popis: Objective To investigate the cause of inner ear disturbances in cases of middle ear cholesteatoma with labyrinthine fistula. Setting University hospital. Study design Prospective case study. Patients Eight patients who were scheduled to undergo surgery for middle ear cholesteatoma with labyrinthine fistula were included in this study. Intervention Imaging analysis was performed using a 3-dimensional fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging sequence. Main outcome measures Three-dimensional FLAIR findings were compared with clinical symptoms associated with inner ear disturbance and surgical observations of the fistula. Results Three-dimensional FLAIR in 6 patients revealed areas of high signal intensity in the inner ears on the affected sides and areas with increased signal after the administration of gadolinium, especially in cases accompanied by acute sensorineural hearing loss. These images were considered to be indicative of breakdown of the blood-labyrinth barrier due to middle ear cholesteatoma. This finding was also present in a patient with no clinical symptoms of inner ear disturbances. Conclusion Three-dimensional FLAIR images of the inner ear are valuable in evaluating labyrinthine fistula in patients with cholesteatoma. Future studies are needed to better understand the role of 3-dimensional FLAIR in predicting the severity of inner ear disturbance.
Databáze: OpenAIRE