Integration of Graphene on AlN Based High Frequency Resonators and Their Functionalization for Biosensing
| Autor: | Jimena Olivares, Bruno Marco, Enrique Iborra, Diego Mejias, Lorena Gordillo, José Miguel Escolano, Marta Clement |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Streptavidin
Materials science Graphene graphene integration Nanotechnology lcsh:A gravimetric biosensor law.invention Resonator chemistry.chemical_compound chemistry Covalent bond law Biotinylation molecule detection Surface modification Molecule lcsh:General Works Biosensor surface functionalization |
| Zdroj: | Proceedings, Vol 1, Iss 4, p 539 (2017) |
| ISSN: | 2504-3900 |
| Popis: | We present the successful integration of graphene on top of AlN-based solidly mounted resonators (SMRs), using a low temperature CVD process and Ni layers as catalyst. We develop a protocol to functionalize the surface of the resonators that starts with a low damage O2 radical plasma treatment of the surface of the devices that introduces a controlled density of defects on the graphene. Then, EDC/NHS chemistry is used to covalently bond streptavidin molecules to the surface of the sensors. Finally, the functionalised biosensors are assessed by analysing their response to biotinylated antibodies. |
| Databáze: | OpenAIRE |
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