An uncommon etiology of anemia: copper deficiency
Autor: | Edwige Kouamou, Alain Stépanian, Fadi Khadra, Dominique de Prost, France Teillet |
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Rok vydání: | 2013 |
Předmět: |
Male
medicine.medical_specialty Anemia Blood count Macrocytosis Folic Acid Deficiency Gastroenterology Diagnosis Differential Internal medicine medicine Humans Medical history Anemia Macrocytic Leukopenia biology business.industry Ceruloplasmin General Medicine Middle Aged medicine.disease Alcoholism Hypertension Etiology biology.protein medicine.symptom Copper deficiency business Copper Follow-Up Studies |
Zdroj: | Annales de biologie clinique. 71:481-484 |
ISSN: | 0003-3898 |
DOI: | 10.1684/abc.2013.0863 |
Popis: | A 58-year-old patient, without any notable medical history, except for alcoholism and treated hypertension, developed anemia and leukopenia with macrocytosis. Folate deficiency was diagnosed and subsequently treated. Despite folate supplementation, the hematological parameters did not normalize. Further diagnosis investigations were led to search for uncommon etiologies of anemia and leukoneutropenia. We diagnosed severe copper deficiency on the basis of decreased plasma levels of copper and ceruloplasmin. Copper supplementation improved blood counts within three months. This case illustrates hematological disorders due to copper deficiency, initially masked by an associated folate deficiency. The copper deficiency etiology was not identified in this case. |
Databáze: | OpenAIRE |
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