Community transmission of hepatitis B virus in Egypt: results from a case-control study in Greater Cairo
| Autor: | Mostafa K. Mohamed, Saeed El Aidi, Adela Paez Jimenez, Nasr El-Sayed, Mai El-Daly, Mohamed Abdel-Hamid, Arnaud Fontanet, Yehia Sultan, Mostafa El-Hoseiny, Noha Sharaf Eldin |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Sexual transmission Epidemiology Health Promotion medicine.disease_cause Barbering Hepatitis B Chronic Orthohepadnavirus Risk Factors Internal medicine Odds Ratio Humans Medicine Hepatitis B Vaccines Risk factor Hepatitis B virus biology business.industry Coitus General Medicine Odds ratio Hepatitis B biology.organism_classification medicine.disease Hepadnaviridae Case-Control Studies Immunology Egypt Female business |
| Zdroj: | International Journal of Epidemiology. 38:757-765 |
| ISSN: | 1464-3685 0300-5771 |
| Popis: | BACKGROUND To identify current risk factors for hepatitis B virus (HBV) transmission in Greater Cairo. METHODS A 1:1 matched case-control study was conducted in two 'fever' hospitals in Cairo. Acute hepatitis B cases were patients with acute hepatitis, positive HBs antigen, and high anti-HBc IgM titres. Control subjects were acute hepatitis A patients (positive anti-HAV IgM) or relatives of patients diagnosed with acute hepatitis C, identified at the same hospitals, with no past HBV infection (negative anti-HBc) and matched to cases on the same age and sex. Conditional logistic regression was used to identify factors associated with acute hepatitis B. RESULTS Between April 2002 and June 2006, 233 cases and 233 controls were recruited to the study. In multivariate analysis, factors associated with an increased HBV risk in males were illiteracy [odds ratio (OR) = 6.1, 95% confidence interval (CI) = 2.8-13.1], shaving at barbers (OR = 2.1, 95% CI = 1.1-3.9) and injecting drug use (IDU) (OR = 3.4, 95% CI = 1.0-11.4). In females, factors associated with an increased HBV risk were illiteracy (OR = 2.2, 95% CI = 1.0-5.0), recent ( |
| Databáze: | OpenAIRE |
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