Mania in Wolfram’s Disease: From Bedside to Bench
| Autor: | Sayantanava Mitra, Seshadri Sekhar Chatterjee, Salil Kumar Pal |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Psychosis medicine.medical_specialty Bipolar Disorder endocrine system diseases Wolfram syndrome Case Report Comorbidity Disease 03 medical and health sciences Behavioral Neuroscience 0302 clinical medicine otorhinolaryngologic diseases medicine Pharmacology (medical) Bipolar disorder Psychiatry Clinical psychiatry business.industry medicine.disease eye diseases Psychiatry and Mental health 030104 developmental biology Schizophrenia medicine.symptom business Mania 030217 neurology & neurosurgery |
| Zdroj: | Clinical Psychopharmacology and Neuroscience |
| ISSN: | 2093-4327 1738-1088 |
| DOI: | 10.9758/cpn.2017.15.1.70 |
| Popis: | Wolfram syndrome is a relatively unexplored entity in clinical psychiatry. Historically, the discovery of a specific WFS1 gene had generated huge fanfare regarding specific genetic causations of psychiatric disorders. While the initial enthusiasm has faded now, association of Wolfram syndrome with psychiatric illnesses like schizophrenia, psychosis and suicidal behavior still remain important for understanding biological underpinnings of such disorders. We report a case of Wolfram syndrome presenting with multiple manic episodes, discuss possible genetic underpinnings for the affective symptoms and then discuss certain issues regarding management. |
| Databáze: | OpenAIRE |
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