A pilot comparison study of four clinician‐rated atopic dermatitis severity scales
| Autor: | J.P. Lazo‐Dizon, Jae Hwan Kim, C.Y. Zhao, A.Q.T. Tran, Benjamin S. Daniel, Matthew Law, Supriya S. Venugopal, Lesley M. Rhodes, Dedee F. Murrell |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Intraclass correlation Dermatology Severity of Illness Index Eczema Area and Severity Index Dermatitis Atopic Severity of illness medicine Humans Prospective Studies Observer Variation Body surface area business.industry Dermatology Life Quality Index Intra-rater reliability Atopic dermatitis medicine.disease Confidence interval Quality of Life Physical therapy Feasibility Studies Female Self Report business |
| Zdroj: | British Journal of Dermatology. 173:488-497 |
| ISSN: | 1365-2133 0007-0963 |
| DOI: | 10.1111/bjd.13846 |
| Popis: | SummaryBackground There are multiple severity outcome measures for atopic dermatitis (AD). There is a need to compare the reliability of these measures. Objectives To compare the inter-rater and intrarater reliability of the objective Scoring Atopic Dermatitis (oSCORAD), Eczema Area and Severity Index (EASI), Six Area, Six Sign Atopic Dermatitis (SASSAD) and Three Item Severity index (TIS); and to analyse the correlation between these outcome measures and the quality-of-life instruments Patient-Orientated Eczema Measurement, Dermatology Life Quality Index and Skindex-29. Methods Twelve patients with AD attended a 1-day scoring exercise by five trained dermatology clinicians. Inter-rater and intrarater reliability were assessed using the intraclass correlation coefficient (ICC). Correlation between clinician-rated and patient-reported measures was analysed using Spearman's rho. Results Regarding inter-rater reliability, EASI and SASSAD showed good reliabilities, with ICCs of 0·730 [95% confidence interval (CI) 0·500–0·900] and 0·680 (95% CI 0·440–0·880), respectively. However, the ICCs were poor for TIS and oSCORAD, with 0·497 (95% CI 0·233–0·785) and 0·498 (95% CI 0·234–0·785), respectively. Separate body surface area (BSA) component analyses showed that the oSCORAD BSA component contributed to its inter-rater variations. Regarding intrarater reliability, EASI and TIS showed excellent ICCs of 0·886 (95% CI 0·744–0·952) and 0·820 (0·614–0·923), respectively, while SASSAD showed a good reliability with an ICC of 0·720 (95% CI 0·424–0·878). However, the intrarater ICC was poor for oSCORAD, with 0·446 (95% CI 0·037–0·730). Regarding correlation with patient-reported measures, only SASSAD demonstrated moderate correlation with Skindex-29 (ρ = 0·611, P = 0·035). Conclusions EASI demonstrated the highest inter-rater and intrarater reliability, supporting it as the optimal AD severity outcome measure. |
| Databáze: | OpenAIRE |
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