Impact of sperm cell source on the results of intracytoplasmic sperm injection
| Autor: | Gohar Rahimi, Therese Skonieczny, Christian Gnoth, Kerstin Friol, Vitaly Markhinin, Beatrice Maxrath, Erhard Godehardt, Judith Roos |
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| Rok vydání: | 2014 |
| Předmět: |
Male
Infertility endocrine system Sperm Retrieval Pregnancy Rate Cryptozoospermia medicine.medical_treatment Fertilization in Vitro Intracytoplasmic sperm injection Male infertility Andrology Pregnancy medicine Humans Ejaculation Sperm Injections Intracytoplasmic Infertility Male reproductive and urinary physiology Sperm motility Retrospective Studies Azoospermia urogenital system business.industry Pregnancy Outcome Obstetrics and Gynecology General Medicine Middle Aged Embryo Transfer medicine.disease Spermatozoa Sperm Testicular sperm extraction Sperm Motility Female business |
| Zdroj: | Archives of Gynecology and Obstetrics. 291:663-669 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-014-3448-5 |
| Popis: | Purpose There is an ongoing debate whether the source of sperm cells, the etiology or the extent of male factor infertility has influence on the outcome of ICSI cycles. Methods The results of intracytoplasmic sperm injection (ICSI) according to the source of spermatozoa in patients with severe male factor infertility were compared in a retrospective study: 249 couples underwent a total of 337 fresh ICSI cycles with the use of fresh motile testicular or fresh motile ejaculated spermatozoa. Results For all variables, there were no statistically significant differences in the ICSI results between both groups. Fertilization rates were 46.8 % for testicular and 47.6 % for ejaculated spermatozoa. Live birth rates per embryo transfer were 20.4 % using testicular spermatozoa and 22.8 % using ejaculated spermatozoa. Conclusions Neither the source of spermatozoa nor the etiology of severe male infertility has relevant impact on the results of ICSI cycles as long as fresh motile, morphologically normal spermatozoa are used. Therefore, in case of cryptozoospermia, we recommend to preferentially use ejaculated spermatozoa to prevent those men from an unnecessary testicular biopsy avoiding risks and costs implied. |
| Databáze: | OpenAIRE |
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