The posterior parietal cortex mediates early offline-rather than online-motor sequence learning
| Autor: | Maike Foerster, Vanessa Krause, Bettina Pollok, Ariane Keitel, Katharina Otto, Geraldine Moshiri |
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| Rok vydání: | 2020 |
| Předmět: |
Serial reaction time
Adult Male Cognitive Neuroscience medicine.medical_treatment education Posterior parietal cortex Experimental and Cognitive Psychology Transcranial Direct Current Stimulation 050105 experimental psychology 03 medical and health sciences Behavioral Neuroscience Young Adult 0302 clinical medicine Parietal Lobe medicine Reaction Time Humans Learning 0501 psychology and cognitive sciences Motor skill Neuronal Plasticity Transcranial direct-current stimulation 05 social sciences Motor Cortex Motor control Offline learning Female Primary motor cortex Psychology Motor learning Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Neuropsychologia. 146 |
| ISSN: | 1873-3514 |
| Popis: | Learning of new motor skills occurs particularly during training on a task (i.e. online) but has been observed between training-blocks lasting up to days after the end of the training (i.e. offline). Offline-learning occurs as further improvement in task performance indicated by increased accuracy and/or faster responses as well as less interference with respect to a distracting condition. Successful motor learning requires the functional interplay between cortical as well as subcortical brain areas. While the involvement of the primary motor cortex in online-as well as early offline-learning is well established, the functional significance of the posterior parietal cortex (PPC) is less clear. Since the PPC may act as sensory-motor interface, a causal involvement in motor learning is conceivable. In order to characterize the functional significance of the left PPC for motor sequence learning, transcranial direct current stimulation (tDCS) was applied either immediately prior to, during or immediately after training on a serial reaction time task (SRTT) in a total of 54 healthy volunteers. While the analysis did not provide evidence for a significant modulation of reaction times during SRTT training (i.e. online-learning), cathodal tDCS decelerated reaction times of the learned sequences as compared to anodal and sham stimulation 30 min after the end of training. The findings suggest that cathodal tDCS over the left parietal cortex interferes with the reproduction of learned sequences. |
| Databáze: | OpenAIRE |
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